This artificial pancreas could automate insulin delivery for diabetics


The need for diabetics on insulin to regularly test their blood to monitor glucose levels and administer the appropriate amount of insulin could soon be a thing of the past if an artificial pancreas that can do this automatically becomes widespread in use. — dpa

A new artificial pancreas could automate the process of keeping blood sugar levels in check for people with type 2 diabetes, researchers have said.

A new small study suggests patients can keep their blood sugar levels at a healthy level using the device, which requires no human input.

Patients in England and Wales with uncontrolled type 1 diabetes should soon be eligible to have a similar device fitted in the United Kingdom’s National Health System (NHS).

In draft guidance, the UK National Institute for Health and Care Excellence (Nice) said patients struggling to manage their blood sugar levels could benefit from a “hybrid closed loop” system that delivers the appropriate level of insulin to the body without the need for constant monitoring.

Experts said the device could make complications such as amputations and blindness, a “thing of the past” for patients with type 1 diabetes.

The new study, from academics at the University of Cambridge, looked at a slightly different system – a fully closed loop system – in patients with type 2 diabetes.

Researchers from the Wellcome-MRC Institute of Metabolic Science at the university developed an artificial pancreas that can help maintain healthy glucose levels and was tested among 26 type 2 diabetes patients.

Half the group trialled the artificial pancreas for eight weeks and then switched to standard therapy of multiple daily insulin injections.

The second group had standard therapy for the first eight weeks and then switched to the new system.

Researchers used several assessments to test the artificial pancreas, including the proportion of time patients had healthy blood sugar levels.

On average, patients using the artificial pancreas spent two-thirds (66%) of their time within the target range – double that while on the control (32%), according to the study published in the journal Nature Medicine.

Study co-lead Dr Charlotte Boughton said: “Many people with type 2 diabetes struggle to manage their blood sugar levels using the currently available treatments, such as insulin injections.

“The artificial pancreas can provide a safe and effective approach to help them and the technology is simple to use and can be implemented safely at home.”

Principal study investigator Dr Aideen Daly added: “One of the barriers to widespread use of insulin therapy has been concern over the risk of severe ‘hypos’ – dangerously low blood sugar levels.

“But we found that no patients on our trial experienced these and patients spent very little time with blood sugar levels lower than the target levels.” – PA Media/dpa

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