A certain class of PFAS was discovered to have a weakness that can be exploited to make them harmless. — AFP
"Forever chemicals" used in daily items like non-stick pans have long been linked to serious health issues – a result of their toxicity and extreme resistance to being broken down as waste products.
Chemists in the United States and China on Aug 18 (2022) said they had finally found a breakthrough method to degrade these polluting compounds – referred to as PFAS – using relatively low temperatures and common reagents.
Their results were published in the journal Science, potentially offering a solution to a longstanding source of harm to the environment, livestock and humans.
"It really is why I do science – so that I can have a positive impact on the world," senior author William Dichtel of Northwestern University in the US told reporters during a news conference.
PFAS, or per- and polyfluoroalkyl substances, were first developed in the 1940s and are now found in a variety of products, including non-stick pans, water-resistant textiles and fire suppression foams.
Over time, the pollutants have accumulated in the environment, entering the air, soil, groundwater, and lakes and rivers, as a result of industrial processes and from leaching through landfills.
A study published in early August (2022) by Stockholm University scientists found rainwater everywhere on the planet is unsafe to drink because of PFAS contamination.
Chronic exposure to even low levels has been linked to liver damage, high cholesterol, reduced immune responses, low birth weights and several kinds of cancer.
Although PFAS chemicals can be filtered out of water, there are few good solutions for how to dispose of them once they have been removed.
Current methods to destroy PFAS require harsh treatments, such as incineration at extremely high temperatures or irradiating them with ultrasonic waves.
And incineration isn't always foolproof, with one New York plant found to still be releasing some of the compounds into the air through smoke.
PFAS' indestructability comes from their carbon-flouride bonds – one of the strongest types of bonds in organic chemistry.
Fluorine is the most electronegative element and wants to gain electrons, while carbon is keen to share them, so once together, they don't want to "let go" of each other.
PFAS molecules contain long chains of these bonds, but the research team was able to identify a glaring weakness common to a certain class of PFAS.
At one end of the molecule, there is a group of charged oxygen atoms that can be targeted using a common solvent and reagent at mild temperatures of 80-120°C, decapitating the head group and leaving behind a reactive tail.
"Once that happens, that provides access to previously unrecognized pathways that cause the entire molecule to fall apart in a cascade of complex reactions," said Dichtel, adding that that will ultimately create benign end products.
A second part of the study involved using powerful computational methods to map out the quantum mechanics behind the chemical reactions the team performed to destroy the molecules.
The new knowledge could eventually guide further improvements to the method.
The current study focused on 10 PFAS chemicals, including a major pollutant called GenX, which, for example, has contaminated the Cape Fear River in North Carolina, a water source for 350,000 people in the US.
But it represents just the tip of the iceberg as the US Environmental Protection Agency (EPA) has identified more than 12,000 PFAS chemicals.
"There are other classes that don't have the same Achilles' heel, but each one will have its own weakness," said Dichtel in a statement.
"If we can identify it, then we know how to activate it to destroy it." – AFP Relaxnews
