Smaller dose, bigger punch

Global health goal: Some of the production technology advances will hinge on changing the shape of the genetic material in mRNA vaccines. — The Straits Times/ANN

A team of researchers is working on the next generation of mRNA vaccines that could have doses up to 100 times smaller than current ones and be cheaper to manufacture.

Some of the production technology advances will hinge on changing the shape of the genetic material in mRNA vaccines – the technology used in Pfizer and Moderna Covid-19 vaccines – with the researchers looking at replacing the use of straight strands of RNA in favour of the more stable circular RNA.