New vulnerability in SARS-CoV-2 exposed: study


By Xu Jing
  • World
  • Wednesday, 12 Aug 2020

CHICAGO, Aug. 11 (Xinhua) -- Northwestern University (NU) researchers have uncovered a new vulnerability in the novel coronavirus' infamous spike protein, pointing to a relatively simple, potential treatment pathway.

Using nanometer-level simulations, the researchers discovered a positively charged site, known as the polybasic cleavage site, located 10 nanometers from the actual binding site on the spike protein. The positively charged site allows strong bonding between the virus protein and the negatively charged human-cell receptors.

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