Weight returns four times faster after stopping weight-loss drugs

Compared to lifestyle changes like eating healthier and exercising regularly, those who just take weight-loss drugs tend to pile back the kilos faster after stopping them. — Freepik

When people stop taking the new generation of weight-loss drugs, they pile back the kilos four times faster than they would after ending diet and exercise regimes, new research found on Jan 8 (2026).

But this was mostly because they lost so much weight in the first place, according to the British researchers who conducted the largest and most up-to-date review of the subject.