Nvidia-backed Iambic Therapeutics launches IPO as biotechs buck market gloom


An Nasdaq logo, in this illustration taken September 28, 2026. REUTERS/Dado Ruvic/Illustration

Oct 8 (Reuters) - Nvidia-backed Iambic Therapeutics, which uses AI to develop drugs, ⁠is aiming to raise up to $159.4 million in its USIPO, as ‌the biotech sector emerges as a bright spot in an otherwise lackluster market.

The initial public offering would value the drugmaker at up to $805.8 million — towards the top of its indicated price range — ​based on the number of outstanding shares listed ⁠in its prospectus, a regulatory filing ⁠showed on Tuesday.

AI-driven drug discovery is among the few areas where the technology's ⁠promise ‌is translating into growing investor interest, as biotech companies use it to identify drug candidates and speed up parts of the development process.

Iambic ⁠is marketing roughly 9.38 million shares at $15 to $17 apiece. ​Investment firms ARK Investment ‌Management and Duquesne Family Office have indicated interest in purchasing shares ⁠worth $60 million.

Founded in ​2019 as Entos, Iambic is advancing a pipeline of drug candidates developed using its AI platform to treat solid tumors. It has partnerships with some top pharma companies, ⁠including AbbVie and Takeda Pharmaceutical.

"I would characterize it ​as a clinical-stage biotech company with an AI-enhanced drug discovery platform, rather than a pure AI play," said Kat Liu, vice president at IPOX. The valuation depends primarily ⁠on pipeline strength and the probability of eventual approval and commercialization, Liu added.

A successful listing would set Iambic apart in a fall IPO market hit by a string of delays as rising Treasury yields and market volatility make investors ​more cautious.

Concerns over an overheating AI trade and persistent ⁠geopolitical tensions have further dampened appetite, leaving biotech among the few areas still ​drawing interest.

Iambic is aiming to trade on the ‌Nasdaq under the ticker symbol "IAM" after the ​offering. J.P.Morgan, Jefferies, BofA Securities and Citigroup are the lead underwriters.

(Reporting by Manya Saini in Bengaluru; Editing by Maju Samuel and Joyjeet Das)

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