Eli Lilly extends partnership with Insilico Medicine for AI-powered drug discovery


FILE PHOTO: Eli Lilly and Company’s logo is displayed during a press conference in Houston, Texas, U.S., September 23, 2025. REUTERS/Antranik Tavitian/File Photo

March 29 (Reuters) - Insilico ⁠Medicine said on Sunday it is ⁠partnering with Eli Lilly in a ‌deal worth up to $2.75 billion, expanding an existing collaboration on AI-powered drug discovery.

Lilly will use Insilico's ​AI engine and receive an ⁠exclusive worldwide license ⁠for the development, manufacturing, and commercialization of certain ⁠oral ‌treatments currently in preclinical development.

Under the terms of the agreement, ⁠Insilico is eligible to receive a $115 million ​upfront ‌payment, followed by development, regulatory, and commercial ⁠milestones ​that could bring the total deal value to approximately $2.75 billion, plus tiered royalties on ⁠future sales.

"By deploying AI technologies ​that scale from biomarkers to life models, world models of human and animal life, we ⁠can identify multi-purpose targets driving multiple diseases at the same time," said Alex Zhavoronkov, founder and CEO of Insilico Medicine.

Lilly ​and Insilico had signed ⁠a research collaboration in November, broadening a ​partnership that began with ‌an AI-based software licensing ​agreement in 2023.

(Reporting by Christy Santhosh in Bengaluru; Editing by Tasim Zahid)

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