At least seven dead after UPS plane crashes in fireball on takeoff from Louisville, Kentucky

Smoke rises from the wreackage of a UPS MD-11 cargo jet after it crashed on departure from Louisville Muhammad Ali International Airport in Louisville, Kentucky, U.S. November 4, 2025. Jeff Faughender/USA Today Network via REUTERS.

(Reuters) -A UPS wide-body cargo plane crashed on Tuesday and erupted into a fireball moments after takeoff from the international airport in Louisville, Kentucky, killing seven, including all three aboard, and injuring 11 on the ground, officials said.

Flames from the crash, shortly before sundown, ignited a string of fires in an industrial corridor adjacent to the airport, forcing authorities to halt flight operations through the night, the officials said.