Explainer: Making a new generation of 'guided-missile' cancer drugs work


  • World
  • Monday, 06 Jan 2020

FRANKFURT (Reuters) - A class of treatments known as antibody-drug conjugates (ADC) combine cancer-tracking proteins with powerful cell toxins. The therapies are getting a fresh start as dozens of drugmakers test a record number of new compounds in people.

Nearly 20 years after the first ADC, Pfizer's Mylotarg, was approved, developers say they are now getting a handle on the technology that was long seen as an elegant concept, but one that presented many clinical challenges.

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