Daniil Medvedev, Iga Swiatek heavy U.S. Open favorites

Tennis - ATP 250 - Los Cabos Open - Cabo Sports Complex, San Jose del Cabo, Mexico - August 5, 2022 Russia's Daniil Medvedev reacts during his semifinal match against Serbia's Miomir Kecmanovic REUTERS/Carlos Perez Gallardo/Files

Top seeds Daniil Medvedev and Iga Swiatek were heavy favorites to claim their respective titles as play began at the U.S. Open on Monday.

Medvedev was the +260 favorite at BetMGM to defend the men's title ahead of Spaniards Rafael Nadal (+400) and Carlos Alcaraz (+550). Medvedev claimed his first career Grand Slam title at last year's U.S. Open, where he denied Novak Djokovic from winning the "Calendar Slam."