NEW YORK (Reuters) - Defending champion Naomi Osaka and third seed Stefanos Tsitsipas became high-profile casualties in the third round of the U.S. Open on Friday as two 18-year-olds announced themselves on the big stage by advancing to the last-16 for the first time.
Two-time champion Osaka's title defence ended in tears as she suffered a stunning 5-7 7-6(2) 6-4 loss to Canadian Leylah Fernandez and the Japanese said she planned to take a break from the sport.
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