AstraZeneca partner sticks with two full dose regimen in COVID trials in India


  • World
  • Wednesday, 02 Dec 2020

An employee in personal protective equipment (PPE) removes vials of AstraZeneca's COVISHIELD, coronavirus disease (COVID-19) vaccine from a visual inspection machine inside a lab at Serum Institute of India, in Pune, India, November 30, 2020. Picture taken November 30, 2020. REUTERS/Francis Mascarenhas

PUNE (Reuters) - Serum Institute of India, which has partnered with AstraZeneca to manufacture its COVID-19 vaccine, will continue to test a two full dose regimen of the shot despite it showing a lower success rate than a half and full dose regimen in pivotal trials, a top executive told Reuters.

The British drugmaker has said its COVID-19 vaccine could be up to 90% effective if administered as a half dose followed by a full dose, but some scientists have questioned the robustness of that result because only a few thousand people were given that regimen in late-stage UK trials.

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