Govt still mulling using costly Qdenga vaccine


KUALA LUMPUR: Despite the conditional registration approval for a dengue vaccine recently, the government still needs time to consider its inclusion in the National Immunisation Programme, says Health Minister Datuk Seri Dr Dzulkefly Ahmad.

This was mainly due to the high cost of the Qdenga vaccine, of which the National Pharmaceutical Regulatory Agency (NPRA) had approved a conditional registration earlier in February.

“The NPRA has given conditional registration to the dengue vaccine manufactured by Takeda (Takeda Pharmaceutical) and it is already available in the private sector for the public.

“The issue is when we can include it in the National Immunisation Programme. It will take a long time to do so as we need to take into account the budget allocation (for the vaccines),” he told reporters at Rumah Keluarga Angkatan Tentera (RKAT) here yesterday after launching the national-level Program Gotong Royong Mega Perangi Aedes 1.0 in conjunction with the Asean Dengue Day 2024.

On Feb 8, the 393rd Drug Control Authority meeting approved the conditional registration for the Qdenga dengue vaccine, which is used to prevent dengue fever in people aged four and above.

It was reported that Takeda would sell the vaccine at a discounted rate in emerging markets at a one-third discount of its European pricing.

The vaccine was approved for use in Indonesia where it was priced at US$80 (RM373) for a course of two shots.

Having a closer look: Dzulkefly looking at samples of Wolbachia mosquitoes displayed at the launch of the Gotong Royong Mega Perangi Aedes event here yesterday. — Bernama
Having a closer look: Dzulkefly looking at samples of Wolbachia mosquitoes displayed at the launch of the Gotong Royong Mega Perangi Aedes event here yesterday. — Bernama

Meanwhile, Dzulkefly said his ministry has submitted the request to get an allocation to expand the Wolbachia mosquitoes project in the fight against Aedes.

“We would like to see a national rollout (of Wolbachia mosquitoes project). We will ensure an allocation through Budget 2025.

“We have submitted a request for the project allocation as part of the Cabinet Committee to Combat Dengue programme.

“For the time being, each Wolbachia mosquito costs us 50sen, that’s how valuable it is,” he said.

As of last December, Wolbachia-infected mosquitoes have been released in 35 localities in several states such as Kuala Lumpur, Selangor and Penang among others.

Dzulkefly said since the introduction of the project in 2019, 19 out of the total localities had recorded a decrease in dengue cases between 43% and 100%.

“The successful implementation of the programme has made us among the leaders in the Wolbachia mosquitoes project.

“We’ve received visits from other countries (to learn about the project), for example, a delegation from Burkina Faso who took part in a crash-course programme with us,” he added.

Wolbachia is a bacterium and a form of biological control that is naturally occurring in 60%-70% of insects, spiders and nematodes.

It is usually introduced into Aedes mosquitoes to prevent the transmission of dengue viruses.

The Wolbachia bacteria stops the dengue virus from replicating, so the mosquito does not spread the virus when it bites.

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