The fatal crash happened on National Road 78 in Koh Nhek district, said Khlout Sokhea, police chief of Koh Nhek district, adding that reckless driving was blamed for the accident.
"Three people were pronounced dead at the scene and 10 others were injured, including one in severe condition," he told Xinhua.
Among the dead were two men and a woman, he said, adding that for the injured, they had been rushed to the provincial hospital.
Casualties from road traffic accidents remain high in the South-East Asian nation.
During the first six months of 2020, a total of 861 people were killed and 2,449 others were wounded in road crashes across the kingdom, according to a government report.
The Covid-19 pandemic, however, looks to be under control in the country.
Cambodia on Friday confirmed five new Covid-19 cases including two US diplomats, raising the total number of infections in the kingdom to 171, according to the Health Ministry.
The South-East Asian country said that from the 171 confirmed virus cases, with 133 patients cured and 38 hospitalised. - Xinhua
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