Simeone seeks first Liga win over Barca in his 300th game

Football Soccer - Bayer Leverkusen v Atletico Madrid - UEFA Champions League Round of 16 First Leg - BayArena, Leverkusen, Germany - 21/2/17 Atletico Madrid coach Diego Simeone Reuters / Wolfgang Rattay Livepic - RTSZPA2

MADRID (Reuters) - The toughness and guile that made Diego Simeone a great player has been there for all to see in his time as manager of Atletico Madrid, and the Argentinian marks his 300th game at the club with a major challenge on Sunday against Barcelona.

Simeone's team has yet to beat Barca in domestic competition, but they broke the 10-year duopoly of Barcelona and Real Madrid in La Liga in the 2013-14 campaign - the club's first league crown for 18 years.