The rumbling 3,763-m-high volcano registered a powerful eruption from 11:28 pm Friday (1:28pm Saturday Malaysia time).
In the afternoon, explosions generated ash columns 4,500m above sea level, 500m less than in the morning. The longest of three lava flows so far stretched 1,600m.
Although the ash could travel as far as Guatemala City, it has not yet reached the capital, instead affecting populations in the four departments near the volcano.
Earlier, it pumped out a series of moderate and strong explosions, according to the National Institute of Seismology, Volcanology, Meteorology and Hydrology.
In addition to Fuego, the Central American country has two other active volcanos: Santiaguito in the west and Pacaya in the south, just 30km from the capital.
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